HBV Target gene Detail Information

> GLI3 Gene Search Result

Gene Information

Gene Name	GLI3
Gene ID	2737
Gene Full Name	GLI family zinc finger 3
Gene Alias	PHS; ACLS; GCPS; PAPA; PAPB; PAP-A; PAPA1; PPDIV; GLI3FL; GLI3-190
Transcripts	ENSG00000106571
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nucleoli;Vesicles;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Transcription factors
Gene Function	Oncogene
Uniport_ID	P10071
HGNC ID	HGNC:4319
VEGA ID	OTTHUMG00000023630
OMIM ID	165240
String ID	9606.ENSP00000379258
PharmGKB ID	PA28722

Target gene [GLI3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005645	chr7	6	30	14	50	View
1016078	chr7	2			2	View
1400310	chr7	12	1	4	17	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GLI3 expression and immune infiltrating cell level correlation result in HBV+ samples
GLI3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).