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HBV Target gene Detail Information

> GLI2 Gene Search Result


Gene Information
Gene Name GLI2
Gene ID 2736
Gene Full Name GLI family zinc finger 2
Gene Alias CJS; HPE9; PHS2; THP1; THP2
Transcripts ENSG00000074047
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoli;Nucleoplasm;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Transcription factors
Gene Function Oncogene
Uniport_ID P10070
HGNC ID HGNC:4318
VEGA ID OTTHUMG00000153741
OMIM ID 165230
String ID 9606.ENSP00000390436
PharmGKB ID PA28721
Target gene [GLI2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000303 chr2 2786 2556 1139 6481 View
1000304 chr2 2786 2556 1139 6481 View
1000305 chr2 2786 2556 1139 6481 View
1000306 chr2 2786 2556 1139 6481 View
1000307 chr2 2786 2556 1139 6481 View
1000308 chr2 2786 2556 1139 6481 View
1002261 chr2 34 46 226 306 View
1002600 chr2 80 105 67 252 View
1003901 chr2 20 45 38 103 View
1004019 chr2 78 15 6 99 View
1004474 chr2 19 7 54 80 View
1004732 chr2 67 3 70 View
1005664 chr2 35 8 7 50 View
1005665 chr2 35 8 7 50 View
1006558 chr2 15 18 4 37 View
1006559 chr2 15 18 4 37 View
1006628 chr2 28 8 36 View
1006650 chr2 21 9 6 36 View
1007177 chr2 22 8 30 View
1007261 chr2 27 2 29 View
1007881 chr2 15 3 6 24 View
1008454 chr2 11 10 21 View
1010223 chr2 9 4 13 View
1010810 chr2 9 2 11 View
1012019 chr2 8 8 View
1012902 chr2 5 1 6 View
1012903 chr2 5 1 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of GLI2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
GLI2 expression: Low -> High
Lollipop of GLI2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of GLI2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GLI2 expression and immune infiltrating cell level correlation result in HBV+ samples
GLI2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).