HBV Target gene Detail Information

> GLDC Gene Search Result

Gene Information

Gene Name	GLDC
Gene ID	2731
Gene Full Name	glycine decarboxylase
Gene Alias	GCE; GCSP; HYGN1
Transcripts	ENSG00000178445
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P23378
HGNC ID	HGNC:4313
VEGA ID	OTTHUMG00000019524
OMIM ID	238300
String ID	9606.ENSP00000370737
Drugbank ID	BE0000618
PharmGKB ID	PA28716

Target gene [GLDC] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010276	chr9	13			13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GLDC expression and immune infiltrating cell level correlation result in HBV+ samples
GLDC expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).