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HBV Target gene Detail Information

> GLB1 Gene Search Result


Gene Information
Gene Name GLB1
Gene ID 2720
Gene Full Name galactosidase beta 1
Gene Alias EBP; ELNR1; MPS4B
Transcripts ENSG00000170266
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;Golgi apparatus;
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID P16278
HGNC ID HGNC:4298
VEGA ID OTTHUMG00000155781
OMIM ID 611458
String ID 9606.ENSP00000306920
Drugbank ID BE0010418
PharmGKB ID PA28709
Target gene [GLB1] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 22082274 I195M
S
 View
2 22082274 M204I
RT
 View
3 22082274 M204V
RT
 View
4 22082274 W196L
S
 View

Target gene [GLB1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006561 chr1 25 9 2 36 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GLB1 expression and immune infiltrating cell level correlation result in HBV+ samples
GLB1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).