HIV Target gene Detail Information

> GK Gene Search Result

Gene Information

Gene Name	GK
Gene ID	2710
Gene Full Name	glycerol kinase
Gene Alias	GK1; GKD
Transcripts	ENSG00000198814
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P32189
HGNC ID	HGNC:4289
VEGA ID	OTTHUMG00000021328
OMIM ID	300474
String ID	9606.ENSP00000401720
PharmGKB ID	PA28700

Target gene [GK] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004314	chr7	3	41	2	46	View
4006391	chrX	24	1		25	View
4016509	chr2				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GK expression and immune infiltrating cell level correlation result in HIV+ samples
GK expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GK expression and immune infiltrating cell level correlation result in HIV+ samples
GK expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).