HBV Target gene Detail Information

> GJB3 Gene Search Result

Gene Information

Gene Name	GJB3
Gene ID	2707
Gene Full Name	gap junction protein beta 3
Gene Alias	EKV; CX31; DFNA2; EKVP1; DFNA2B
Transcripts	ENSG00000188910
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cell Junctions;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	O75712
HGNC ID	HGNC:4285
VEGA ID	OTTHUMG00000004051
OMIM ID	603324
String ID	9606.ENSP00000362464
PharmGKB ID	PA28696

Target gene [GJB3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008548	chr1	17	3		20	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GJB3 expression and immune infiltrating cell level correlation result in HBV+ samples
GJB3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).