HIV Target gene Detail Information

> GIT2 Gene Search Result

Gene Information

Gene Name	GIT2
Gene ID	9815
Gene Full Name	GIT ArfGAP 2
Gene Alias	PKL; CAT2; CAT-2
Transcripts	ENSG00000139436
Virus	HIV
Gene Type	protein coding
HPA Location Info	Microtubules;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q14161
HGNC ID	HGNC:4273
VEGA ID	OTTHUMG00000169313
OMIM ID	608564
String ID	9606.ENSP00000347464
PharmGKB ID	PA28684

Target gene [GIT2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001337	chr12	13	147	16	176	View
4007655	chr12	15	3		18	View
4009010	chr12	3		10	13	View
4010627	chr12	6	2		8	View
4010826	chr12	4	4		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GIT2 expression and immune infiltrating cell level correlation result in HIV+ samples
GIT2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GIT2 expression and immune infiltrating cell level correlation result in HIV+ samples
GIT2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).