HIV Target gene Detail Information

> GIMAP8 Gene Search Result

Gene Information

Gene Name	GIMAP8
Gene ID	155038
Gene Full Name	GTPase, IMAP family member 8
Gene Alias	IAN6; IAN9; IANT; IAN-9
Transcripts	ENSG00000171115
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8ND71
HGNC ID	HGNC:21792
VEGA ID	OTTHUMG00000158327
OMIM ID	616962
String ID	9606.ENSP00000305107
PharmGKB ID	PA128394762

Target gene [GIMAP8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001421	chr7	97	62	8	167	View
4003045	chr7	50	16	5	71	View
4009348	chr7	9	3		12	View
4010073	chr7	10			10	View
4010513	chr7	9			9	View
4010610	chr7	8			8	View
4012132	chr7	5			5	View
4015145	chr7		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GIMAP8 expression and immune infiltrating cell level correlation result in HIV+ samples
GIMAP8 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GIMAP8 expression and immune infiltrating cell level correlation result in HIV+ samples
GIMAP8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).