HIV Target gene Detail Information

> GIMAP1 Gene Search Result


Gene Information
Gene Name GIMAP1
Gene ID 170575
Gene Full Name GTPase, IMAP family member 1
Gene Alias IAN2; IMAP1; HIMAP1; IMAP38
Transcripts ENSG00000213203
Virus HIV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Uniport_ID Q8WWP7
HGNC ID HGNC:23237
VEGA ID OTTHUMG00000157489
OMIM ID 608084
String ID 9606.ENSP00000302833
PharmGKB ID PA134978698
Target gene [GIMAP1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001185 chr7 176 11 11 198 View
4001903 chr7 24 4 96 124 View
4005889 chr7 28 1 29 View
4006791 chr7 23 23 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of GIMAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
GIMAP1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of GIMAP1 expression and immune infiltrating cell level correlation result in HIV+ samples
GIMAP1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).