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HBV Target gene Detail Information

> GHR Gene Search Result


Gene Information
Gene Name GHR
Gene ID 2690
Gene Full Name growth hormone receptor
Gene Alias GHBP; GHIP
Transcripts ENSG00000112964
Virus HBV
Gene Type protein coding
HPA Location Info Cytoplasmic bodies;Cytosol;Plasma membrane;Predicted to be secreted;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, FDA approved drug targets, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID P10912
HGNC ID HGNC:4263
VEGA ID OTTHUMG00000094791
OMIM ID 600946
String ID 9606.ENSP00000483403
Drugbank ID BE0000075
PharmGKB ID PA28674
Target gene [GHR] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010170 chr5 13 13 View
1010363 chr5 8 4 12 View
1011100 chr5 10 10 View
1013861 chr5 1 2 1 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GHR expression and immune infiltrating cell level correlation result in HBV+ samples
GHR expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).