HBV Target gene Detail Information

> GGNBP2 Gene Search Result


Gene Information
Gene Name GGNBP2
Gene ID 79893
Gene Full Name gametogenetin binding protein 2
Gene Alias DIF3; LZK1; DIF-3; LCRG1; ZFP403; ZNF403
Transcripts ENSG00000275099
Virus HBV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;
HPA Protein Class Info Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q9H3C7
HGNC ID HGNC:19357
VEGA ID OTTHUMG00000191227
OMIM ID 612275
String ID 9606.ENSP00000478220
PharmGKB ID PA162389409
Target gene [GGNBP2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000237 chr17 3029 301 259 3589 View
1000250 chr17 2982 295 233 3510 View
1004733 chr17 68 1 1 70 View
1402504 chr17 68 1 1 70 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GGNBP2 expression and immune infiltrating cell level correlation result in HBV+ samples
GGNBP2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).