HBV Target gene Detail Information

> GGNBP2 Gene Search Result

Gene Information

Gene Name	GGNBP2
Gene ID	79893
Gene Full Name	gametogenetin binding protein 2
Gene Alias	DIF3; LZK1; DIF-3; LCRG1; ZFP403; ZNF403
Transcripts	ENSG00000275099
Virus	HBV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;
HPA Protein Class Info	Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q9H3C7
HGNC ID	HGNC:19357
VEGA ID	OTTHUMG00000191227
OMIM ID	612275
String ID	9606.ENSP00000478220
PharmGKB ID	PA162389409

Target gene [GGNBP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000237	chr17	3029	301	259	3589	View
1000250	chr17	2982	295	233	3510	View
1004733	chr17	68	1	1	70	View
1402504	chr17	68	1	1	70	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GGNBP2 expression and immune infiltrating cell level correlation result in HBV+ samples
GGNBP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).