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HBV Target gene Detail Information

> GGH Gene Search Result


Gene Information
Gene Name GGH
Gene ID 8836
Gene Full Name gamma-glutamyl hydrolase
Gene Alias GH
Transcripts ENSG00000137563
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q92820
HGNC ID HGNC:4248
VEGA ID OTTHUMG00000164365
OMIM ID 601509
String ID 9606.ENSP00000260118
Drugbank ID BE0000265
PharmGKB ID PA432
Target gene [GGH] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007893 chr8 10 10 3 23 View
1012070 chr8 7 7 View
1012509 chr8 6 6 View
1012512 chr8 6 6 View
1012525 chr8 6 6 View
1014404 chr8 3 3 View
1015231 chr8 2 2 View
1016235 chr8 1 1 View
1016263 chr8 1 1 View
1016264 chr8 1 1 View
1016265 chr8 1 1 View
1016266 chr8 1 1 View
1403532 chr8 1 1 View
1403533 chr8 6 6 View
1403534 chr8 1 1 View
1403535 chr8 3 3 View
1403536 chr8 2 2 View
1403537 chr8 1 1 View
1403538 chr8 7 7 View
1403539 chr8 10 10 3 23 View
1403540 chr8 1 1 View
1403541 chr8 1 1 View
1403542 chr8 6 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GGH expression and immune infiltrating cell level correlation result in HBV+ samples
GGH expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).