HBV Target gene Detail Information

> GFRAL Gene Search Result

Gene Information

Gene Name	GFRAL
Gene ID	389400
Gene Full Name	GDNF family receptor alpha like
Gene Alias	GRAL; UNQ9356; C6orf144; bA360D14.1
Transcripts	ENSG00000187871
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q6UXV0
HGNC ID	HGNC:32789
VEGA ID	OTTHUMG00000014900
OMIM ID	617837
String ID	9606.ENSP00000343636
PharmGKB ID	PA145008357

Target gene [GFRAL] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1014100	chr6	2	2		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GFRAL expression and immune infiltrating cell level correlation result in HBV+ samples
GFRAL expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).