HIV Target gene Detail Information

> GFPT1 Gene Search Result

Gene Information

Gene Name	GFPT1
Gene ID	2673
Gene Full Name	glutamine--fructose-6-phosphate transaminase 1
Gene Alias	GFA; GFAT; GFPT; MSLG; CMS12; GFAT1; CMSTA1; GFAT 1; GFAT1m; GFPT1L
Transcripts	ENSG00000198380
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;Nucleoli fibrillar center;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q06210
HGNC ID	HGNC:4241
VEGA ID	OTTHUMG00000152666
OMIM ID	138292
String ID	9606.ENSP00000349860
PharmGKB ID	PA28651

Target gene [GFPT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002446	chr2	89	5		94	View
4009182	chr2	12			12	View
4012598	chr2	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GFPT1 expression and immune infiltrating cell level correlation result in HIV+ samples
GFPT1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GFPT1 expression and immune infiltrating cell level correlation result in HIV+ samples
GFPT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).