HIV Target gene Detail Information

> GFOD1 Gene Search Result

Gene Information

Gene Name	GFOD1
Gene ID	54438
Gene Full Name	glucose-fructose oxidoreductase domain containing 1
Gene Alias	ADG-90; C6orf114
Transcripts	ENSG00000145990
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Plasma membrane;Predicted to be secreted;
HPA Protein Class Info	Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	Q9NXC2
HGNC ID	HGNC:21096
VEGA ID	OTTHUMG00000014276
String ID	9606.ENSP00000368589
PharmGKB ID	PA128394667

Target gene [GFOD1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002486	chr6	69	23		92	View
4004780	chr16	39			39	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of GFOD1 expression and immune infiltrating cell level correlation result in HIV+ samples
GFOD1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of GFOD1 expression and immune infiltrating cell level correlation result in HIV+ samples
GFOD1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).