HTLV1 Target gene Detail Information

> GEMIN6 Gene Search Result

Gene Information

Gene Name	GEMIN6
Gene ID	79833
Gene Full Name	gem nuclear organelle associated protein 6
Transcripts	ENSG00000152147
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8WXD5
HGNC ID	HGNC:20044
VEGA ID	OTTHUMG00000128588
OMIM ID	607006
String ID	9606.ENSP00000281950
PharmGKB ID	PA134952855

Target gene [GEMIN6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000049	chr2	4434	1330	635	6399	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of GEMIN6 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GEMIN6 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of GEMIN6 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GEMIN6 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of GEMIN6 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GEMIN6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).