HBV Target gene Detail Information

> GCSH Gene Search Result

Gene Information

Gene Name	GCSH
Gene ID	2653
Gene Full Name	glycine cleavage system protein H
Gene Alias	GCE; NKH
Transcripts	ENSG00000140905
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P23434
HGNC ID	HGNC:4208
VEGA ID	OTTHUMG00000137626
OMIM ID	238330
String ID	9606.ENSP00000319531
Drugbank ID	BE0002302
PharmGKB ID	PA28621

Target gene [GCSH] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011267	chr16	6	3		9	View
1014407	chr16	2	1		3	View
1403404	chr16	6	3		9	View
1403405	chr16	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GCSH expression and immune infiltrating cell level correlation result in HBV+ samples
GCSH expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).