HBV Target gene Detail Information

> GCOM1 Gene Search Result


Gene Information
Gene Name GCOM1
Gene ID 145781
Gene Full Name GRINL1A complex locus 1
Gene Alias gcom; Gcom2; MYZAP; GRINL1A; MYZAP-POLR2M
Transcripts ENSG00000137878
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
HGNC ID HGNC:26424
VEGA ID OTTHUMG00000176411
String ID 9606.ENSP00000465231
PharmGKB ID PA162389298
Target gene [GCOM1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008035 chr15 22 1 23 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GCOM1 expression and immune infiltrating cell level correlation result in HBV+ samples
GCOM1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).