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HTLV1 Target gene Detail Information

> GCNT2 Gene Search Result


Gene Information
Gene Name GCNT2
Gene ID 2651
Gene Full Name glucosaminyl (N-acetyl) transferase 2 (I blood group)
Gene Alias II; CCAT; IGNT; ULG3; GCNT5; GCNT2C; NACGT1; NAGCT1; CTRCT13; bA421M1.1; bA360O19.2
Transcripts ENSG00000285222
Virus HTLV1
Gene Type protein coding
HPA Location Info Golgi apparatus;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q8N0V5
HGNC ID HGNC:4204
VEGA ID OTTHUMG00000014244
OMIM ID 600429
String ID 9606.ENSP00000368917
PharmGKB ID PA169
Target gene [GCNT2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6002962 chr6 124 56 14 194 View
6009069 chr6 39 39 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of GCNT2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GCNT2 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of GCNT2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GCNT2 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of GCNT2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GCNT2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).