|
Gene Information
|
Gene Name
|
GCLC |
|
Gene ID
|
2729
|
|
Gene Full Name
|
glutamate-cysteine ligase catalytic subunit |
|
Gene Alias
|
GCL; GCS; GLCL; GLCLC |
|
Transcripts
|
ENSG00000001084
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein coding |
|
HPA Location Info
|
Nucleoplasm;Cytosol;Nucleoli; 
|
|
HPA Protein Class Info
|
Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
|
Uniport_ID
|
P48506
|
|
HGNC ID
|
HGNC:4311
|
|
VEGA ID
|
OTTHUMG00000160220
|
|
OMIM ID
|
606857 |
|
String ID
|
9606.ENSP00000229416
|
|
Drugbank ID
|
BE0000166
|
|
PharmGKB ID
|
PA28612
|
Target gene [GCLC] related to VISs 
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6006046 |
chr6 |
52 |
4 |
20 |
76 |
View |
Relationship between gene expression and immune infiltrating cell level
| Data ID |
Disease |
Sample number |
Sample type |
|
GSE55851 (GEO) |
Adult T-cell leukemia |
21 |
Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12) |
|
GSE29312 (GEO) |
HTLV-1 associated myelopathy |
39 |
Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10) |
|
GSE29332 (GEO) |
HTLV-1 associated myelopathy |
35 |
Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10) |
> Dataset: GSE55851
|
|
HeatMap of cell type fractions in all samples
|
Lollipop of GCLC expression and immune infiltrating cell level correlation result in HTLV1+ samples
|
GCLC expression: Low -> High
|
|
|
> Dataset: GSE29312
|
|
HeatMap of cell type fractions in all samples
|
Lollipop of GCLC expression and immune infiltrating cell level correlation result in HTLV1+ samples
|
GCLC expression: Low -> High
|
|
|
> Dataset: GSE29332
|
|
HeatMap of cell type fractions in all samples
|
Lollipop of GCLC expression and immune infiltrating cell level correlation result in HTLV1+ samples
|
GCLC expression: Low -> High
|
|
|
|
|
HTLV1 Target gene Detail Information