HBV Target gene Detail Information

> GC Gene Search Result


Gene Information
Gene Name GC
Gene ID 2638
Gene Full Name GC, vitamin D binding protein
Gene Alias DBP; VDB; GRD3; VDBG; VDBP; GcMAF; DBP/GC; Gc-MAF; DBP-maf; HEL-S-51
Transcripts ENSG00000145321
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Plasma proteins, Predicted secreted proteins
Uniport_ID P02774
HGNC ID HGNC:4187
VEGA ID OTTHUMG00000129915
OMIM ID 139200
String ID 9606.ENSP00000421725
Drugbank ID BE0001141
PharmGKB ID PA28601
Target gene [GC] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003225 chr4 116 17 22 155 View
1015078 chr4 1 2 3 View
1400062 chr4 38 29 121 188 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GC expression and immune infiltrating cell level correlation result in HBV+ samples
GC expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).