HIV Target gene Detail Information

> GBF1 Gene Search Result


Gene Information
Gene Name GBF1
Gene ID 8729
Gene Full Name golgi brefeldin A resistant guanine nucleotide exchange factor 1
Gene Alias ARF1GEF
Transcripts ENSG00000107862
Virus HIV
Gene Type protein coding
HPA Location Info Golgi apparatus;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q92538
HGNC ID HGNC:4181
VEGA ID OTTHUMG00000018955
OMIM ID 603698
String ID 9606.ENSP00000359000
PharmGKB ID PA28595
Target gene [GBF1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002039 chr10 27 50 39 116 View
4002461 chr10 67 14 12 93 View
4002979 chr10 11 33 29 73 View
4005091 chr10 2 21 13 36 View
4011554 chr10 6 6 View
4012193 chr10 4 1 5 View
4014101 chr10 1 1 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of GBF1 expression and immune infiltrating cell level correlation result in HIV+ samples
GBF1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of GBF1 expression and immune infiltrating cell level correlation result in HIV+ samples
GBF1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).