HBV Target gene Detail Information

> GBA3 Gene Search Result


Gene Information
Gene Name GBA3
Gene ID 57733
Gene Full Name glucosylceramidase beta 3 (gene/pseudogene)
Gene Alias CBG; GLUC; KLRP; CBGL1
Transcripts ENSG00000249948
Virus HBV
Gene Type protein coding
HPA Location Info
HGNC ID HGNC:19069
VEGA ID OTTHUMG00000160448
OMIM ID 606619
PharmGKB ID PA134861643
Target gene [GBA3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1012987 chr4 6 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GBA3 expression and immune infiltrating cell level correlation result in HBV+ samples
GBA3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).