HBV Target gene Detail Information

> GATM Gene Search Result


Gene Information
Gene Name GATM
Gene ID 2628
Gene Full Name glycine amidinotransferase
Gene Alias AT; AGAT; CCDS3
Transcripts ENSG00000171766
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID P50440
HGNC ID HGNC:4175
VEGA ID OTTHUMG00000131427
OMIM ID 602360
String ID 9606.ENSP00000379895
Drugbank ID BE0000347
PharmGKB ID PA28590
Target gene [GATM] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004531 chr15 27 42 9 78 View
1008117 chr15 18 4 22 View
1008118 chr15 18 4 22 View
1011172 chr15 4 1 5 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GATM expression and immune infiltrating cell level correlation result in HBV+ samples
GATM expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).