HBV Target gene Detail Information

> GANC Gene Search Result


Gene Information
Gene Name GANC
Gene ID 2595
Gene Full Name glucosidase alpha, neutral C
Transcripts ENSG00000214013
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID Q8TET4
HGNC ID HGNC:4139
VEGA ID OTTHUMG00000130487
OMIM ID 104180
String ID 9606.ENSP00000326227
Drugbank ID BE0004699
PharmGKB ID PA28552
Target gene [GANC] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007195 chr15 28 1 29 View
1017352 chr15 1 1 View
1400980 chr15 28 1 29 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GANC expression and immune infiltrating cell level correlation result in HBV+ samples
GANC expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).