HBV Target gene Detail Information

> GANAB Gene Search Result


Gene Information
Gene Name GANAB
Gene ID 23193
Gene Full Name glucosidase II alpha subunit
Gene Alias G2AN; GIIA; PKD3; GLUII
Transcripts ENSG00000089597
Virus HBV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;
HPA Protein Class Info Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q14697
HGNC ID HGNC:4138
VEGA ID OTTHUMG00000167696
OMIM ID 104160
String ID 9606.ENSP00000340466
Drugbank ID BE0004698
PharmGKB ID PA28551
Target gene [GANAB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1012934 chr11 4 1 1 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GANAB expression and immune infiltrating cell level correlation result in HBV+ samples
GANAB expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).