HTLV1 Target gene Detail Information

> GALNT3 Gene Search Result


Gene Information
Gene Name GALNT3
Gene ID 2591
Gene Full Name polypeptide N-acetylgalactosaminyltransferase 3
Gene Alias HHS; HFTC; HFTC1; GalNAc-T3
Transcripts ENSG00000115339
Virus HTLV1
Gene Type protein coding
HPA Location Info Golgi apparatus;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q14435
HGNC ID HGNC:4125
VEGA ID OTTHUMG00000132157
OMIM ID 601756
String ID 9606.ENSP00000376465
PharmGKB ID PA28538
Target gene [GALNT3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000146 chr2 2200 865 743 3808 View
6015813 chr12 13 13 View
6020297 chr2 7 7 View
6020298 chr2 7 7 View
6020299 chr2 7 7 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of GALNT3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GALNT3 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of GALNT3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GALNT3 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of GALNT3 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GALNT3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).