HBV Target gene Detail Information

> GAD1 Gene Search Result

Gene Information

Gene Name	GAD1
Gene ID	2571
Gene Full Name	glutamate decarboxylase 1
Gene Alias	GAD; SCP; CPSQ1
Transcripts	ENSG00000128683
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;Vesicles;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q99259
HGNC ID	HGNC:4092
VEGA ID	OTTHUMG00000044175
OMIM ID	605363
String ID	9606.ENSP00000350928
Drugbank ID	BE0000378; BE0002165
PharmGKB ID	PA28507

Target gene [GAD1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003596	chr2	14	58	50	122	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GAD1 expression and immune infiltrating cell level correlation result in HBV+ samples
GAD1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).