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HPV Target gene Detail Information

> GABRR1 Gene Search Result


Gene Information
Gene Name GABRR1
Gene ID 2569
Gene Full Name gamma-aminobutyric acid type A receptor rho1 subunit
Transcripts ENSG00000146276
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info FDA approved drug targets, Predicted membrane proteins, Transporters
Uniport_ID P24046
HGNC ID HGNC:4090
VEGA ID OTTHUMG00000015195
OMIM ID 137161
String ID 9606.ENSP00000412673
Drugbank ID BE0000129
PharmGKB ID PA28505
Target gene [GABRR1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5201928 chr6 126 1 127 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of GABRR1 expression and immune infiltrating cell level correlation result in HPV+ samples
GABRR1 expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of GABRR1 expression and immune infiltrating cell level correlation result in HPV+ samples
GABRR1 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of GABRR1 expression and immune infiltrating cell level correlation result in HPV+ samples
GABRR1 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of GABRR1 expression and immune infiltrating cell level correlation result in HPV+ samples
GABRR1 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of GABRR1 expression and immune infiltrating cell level correlation result in HPV+ samples
GABRR1 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of GABRR1 expression and immune infiltrating cell level correlation result in HPV+ samples
GABRR1 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of GABRR1 expression and immune infiltrating cell level correlation result in HPV+ samples
GABRR1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).