HBV Target gene Detail Information

> GABRG3 Gene Search Result

Gene Information

Gene Name	GABRG3
Gene ID	2567
Gene Full Name	gamma-aminobutyric acid type A receptor gamma3 subunit
Transcripts	ENSG00000182256
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q99928
HGNC ID	HGNC:4088
VEGA ID	OTTHUMG00000044462
OMIM ID	600233
String ID	9606.ENSP00000479113
Drugbank ID	BE0003594; BE0008668
PharmGKB ID	PA28502

Target gene [GABRG3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004664	chr15	28	28	17	73	View
1016015	chr15	2			2	View
1017178	chr15	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GABRG3 expression and immune infiltrating cell level correlation result in HBV+ samples
GABRG3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).