HBV Target gene Detail Information

> GABRB3 Gene Search Result

Gene Information

Gene Name	GABRB3
Gene ID	2562
Gene Full Name	gamma-aminobutyric acid type A receptor beta3 subunit
Gene Alias	ECA5; EIEE43
Transcripts	ENSG00000166206
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters
Uniport_ID	P28472
HGNC ID	HGNC:4083
VEGA ID	OTTHUMG00000129231
OMIM ID	137192
String ID	9606.ENSP00000308725
Drugbank ID	BE0002345
PharmGKB ID	PA28497

Target gene [GABRB3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1003439	chr15		132	2	134	View
1003517	chr15	48	23	57	128	View
1010222	chr15		12	1	13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GABRB3 expression and immune infiltrating cell level correlation result in HBV+ samples
GABRB3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).