HBV Target gene Detail Information

> GABRB2 Gene Search Result

Gene Information

Gene Name	GABRB2
Gene ID	2561
Gene Full Name	gamma-aminobutyric acid type A receptor beta2 subunit
Gene Alias	ICEE2
Transcripts	ENSG00000145864
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted membrane proteins, Transporters
Uniport_ID	P47870
HGNC ID	HGNC:4082
VEGA ID	OTTHUMG00000130349
OMIM ID	600232
String ID	9606.ENSP00000274547
Drugbank ID	BE0002346
PharmGKB ID	PA28496

Target gene [GABRB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004147	chr5	5	71	15	91	View
1017042	chr5	1			1	View
1019824	chr5				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of GABRB2 expression and immune infiltrating cell level correlation result in HBV+ samples
GABRB2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).