HBV Target gene Detail Information

> GABRB2 Gene Search Result


Gene Information
Gene Name GABRB2
Gene ID 2561
Gene Full Name gamma-aminobutyric acid type A receptor beta2 subunit
Gene Alias ICEE2
Transcripts ENSG00000145864
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info FDA approved drug targets, Predicted membrane proteins, Transporters
Uniport_ID P47870
HGNC ID HGNC:4082
VEGA ID OTTHUMG00000130349
OMIM ID 600232
String ID 9606.ENSP00000274547
Drugbank ID BE0002346
PharmGKB ID PA28496
Target gene [GABRB2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004147 chr5 5 71 15 91 View
1017042 chr5 1 1 View
1019824 chr5 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GABRB2 expression and immune infiltrating cell level correlation result in HBV+ samples
GABRB2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).