HTLV1 Target gene Detail Information

> GABPB1 Gene Search Result


Gene Information
Gene Name GABPB1
Gene ID 2553
Gene Full Name GA binding protein transcription factor subunit beta 1
Gene Alias E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; GABPB-1; E4TF1-47; E4TF1-53
Transcripts ENSG00000104064
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytoplasmic bodies;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q06547
HGNC ID HGNC:4074
VEGA ID OTTHUMG00000131642
OMIM ID 600610
String ID 9606.ENSP00000220429
PharmGKB ID PA162389163
Target gene [GABPB1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6029213 chr15 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of GABPB1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
GABPB1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).