HBV Target gene Detail Information

> GABBR2 Gene Search Result


Gene Information
Gene Name GABBR2
Gene ID 9568
Gene Full Name gamma-aminobutyric acid type B receptor subunit 2
Gene Alias HG20; GPR51; EIEE59; GPRC3B; NDPLHS; GABABR2; HRIHFB2099
Transcripts ENSG00000136928
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID O75899
HGNC ID HGNC:4507
VEGA ID OTTHUMG00000020345
OMIM ID 607340
String ID 9606.ENSP00000259455
Drugbank ID BE0002340
PharmGKB ID PA28896
Target gene [GABBR2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004228 chr9 71 13 5 89 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of GABBR2 expression and immune infiltrating cell level correlation result in HBV+ samples
GABBR2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).