HBV Target gene Detail Information

> G3BP1 Gene Search Result


Gene Information
Gene Name G3BP1
Gene ID 10146
Gene Full Name G3BP stress granule assembly factor 1
Gene Alias G3BP; HDH-VIII
Transcripts ENSG00000145907
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q13283
HGNC ID HGNC:30292
VEGA ID OTTHUMG00000130123
OMIM ID 608431
String ID 9606.ENSP00000377681
PharmGKB ID PA162389105
Target gene [G3BP1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005715 chr5 12 19 18 49 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of G3BP1 expression and immune infiltrating cell level correlation result in HBV+ samples
G3BP1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).