HBV Target gene Detail Information

> G2E3 Gene Search Result

Gene Information

Gene Name	G2E3
Gene ID	55632
Gene Full Name	G2/M-phase specific E3 ubiquitin protein ligase
Gene Alias	PHF7B; KIAA1333
Transcripts	ENSG00000092140
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Golgi apparatus;Vesicles;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q7L622
HGNC ID	HGNC:20338
VEGA ID	OTTHUMG00000140204
OMIM ID	611299
String ID	9606.ENSP00000206595
PharmGKB ID	PA164720127

Target gene [G2E3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009083	chr14	17			17	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of G2E3 expression and immune infiltrating cell level correlation result in HBV+ samples
G2E3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).