HBV Target gene Detail Information

> FTL Gene Search Result

Gene Information

Gene Name	FTL
Gene ID	2512
Gene Full Name	ferritin light chain
Gene Alias	LFTD; NBIA3
Transcripts	ENSG00000087086
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P02792
HGNC ID	HGNC:3999
VEGA ID	OTTHUMG00000183332
OMIM ID	134790
String ID	9606.ENSP00000366525
Drugbank ID	BE0000085
PharmGKB ID	PA28412

Target gene [FTL] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000185	chr19	2028	1563	1016	4607	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of FTL expression and immune infiltrating cell level correlation result in HBV+ samples
FTL expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).