HIV Target gene Detail Information

> FRS2 Gene Search Result

Gene Information

Gene Name	FRS2
Gene ID	10818
Gene Full Name	fibroblast growth factor receptor substrate 2
Gene Alias	SNT; SNT1; FRS1A; FRS2A; SNT-1; FRS2alpha
Transcripts	ENSG00000166225
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cell Junctions;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8WU20
HGNC ID	HGNC:16971
VEGA ID	OTTHUMG00000169373
OMIM ID	607743
String ID	9606.ENSP00000447241
PharmGKB ID	PA134850063

Target gene [FRS2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007902	chr12	17			17	View
4013085	chr12	4			4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FRS2 expression and immune infiltrating cell level correlation result in HIV+ samples
FRS2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).