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HPV Target gene Detail Information

> FRMPD4 Gene Search Result


Gene Information
Gene Name FRMPD4
Gene ID 9758
Gene Full Name FERM and PDZ domain containing 4
Gene Alias MRX104; PDZD10; PDZK10
Transcripts ENSG00000169933
Virus HPV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q14CM0
HGNC ID HGNC:29007
VEGA ID OTTHUMG00000021138
OMIM ID 300838
String ID 9606.ENSP00000370057
PharmGKB ID PA134977575
Target gene [FRMPD4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5004241 chrX 1 1 View
5004242 chrX 1 1 View
5004699 chrX 0 View
5200072 chrX 0 View
5200512 chrX 1 1 View
5402630 chrX 1 1 View
5402631 chrX 0 View
5402632 chrX 0 View
5402633 chrX 2 2 1 5 View
5404581 chrX 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of FRMPD4 expression and immune infiltrating cell level correlation result in HPV+ samples
FRMPD4 expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of FRMPD4 expression and immune infiltrating cell level correlation result in HPV+ samples
FRMPD4 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of FRMPD4 expression and immune infiltrating cell level correlation result in HPV+ samples
FRMPD4 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of FRMPD4 expression and immune infiltrating cell level correlation result in HPV+ samples
FRMPD4 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of FRMPD4 expression and immune infiltrating cell level correlation result in HPV+ samples
FRMPD4 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of FRMPD4 expression and immune infiltrating cell level correlation result in HPV+ samples
FRMPD4 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of FRMPD4 expression and immune infiltrating cell level correlation result in HPV+ samples
FRMPD4 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).