HIV Target gene Detail Information

> FPR3 Gene Search Result


Gene Information
Gene Name FPR3
Gene ID 2359
Gene Full Name formyl peptide receptor 3
Gene Alias FMLPY; FPRH1; FPRH2; FPRL2; RMLP-R-I; FMLP-R-II; FML2_HUMAN
Transcripts ENSG00000187474
Virus HIV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info G-protein coupled receptors, Predicted membrane proteins
Uniport_ID P25089
HGNC ID HGNC:3828
VEGA ID OTTHUMG00000183502
OMIM ID 136539
String ID 9606.ENSP00000341821
PharmGKB ID PA162388910
Target gene [FPR3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4004817 chr19 23 15 1 39 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of FPR3 expression and immune infiltrating cell level correlation result in HIV+ samples
FPR3 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of FPR3 expression and immune infiltrating cell level correlation result in HIV+ samples
FPR3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).