HBV Target gene Detail Information

> FOXO1 Gene Search Result

Gene Information

Gene Name	FOXO1
Gene ID	2308
Gene Full Name	forkhead box O1
Gene Alias	FKH1; FKHR; FOXO1A
Transcripts	ENSG00000150907
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene & Oncogene
Uniport_ID	Q12778
HGNC ID	HGNC:3819
VEGA ID	OTTHUMG00000016775
OMIM ID	136533
String ID	9606.ENSP00000368880
PharmGKB ID	PA28237

Target gene [FOXO1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001966	chr13	100	141	151	392	View
1001967	chr13	100	140	152	392	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of FOXO1 expression and immune infiltrating cell level correlation result in HBV+ samples
FOXO1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).