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HBV Target gene Detail Information

> FOXM1 Gene Search Result


Gene Information
Gene Name FOXM1
Gene ID 2305
Gene Full Name forkhead box M1
Gene Alias MPP2; HFH11; HNF-3; INS-1; MPP-2; PIG29; FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; TRIDENT; MPHOSPH2
Transcripts ENSG00000111206
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoli;Nucleoli rim;Nucleoplasm;Cytosol;
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins, Transcription factors
Gene Function Oncogene
Uniport_ID Q08050
HGNC ID HGNC:3818
VEGA ID OTTHUMG00000168118
OMIM ID 602341
String ID 9606.ENSP00000342307
PharmGKB ID PA28236
Target gene [FOXM1] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 10534721 C1766G
BCP
G
C
 View
2 24249691 A1762T
C Promoter
G
C
 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of FOXM1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
FOXM1 expression: Low -> High
Lollipop of FOXM1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of FOXM1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of FOXM1 expression and immune infiltrating cell level correlation result in HBV+ samples
FOXM1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).