HPV Target gene Detail Information

> FOXD4L4 Gene Search Result

Gene Information

Gene Name	FOXD4L4
Gene ID	349334
Gene Full Name	forkhead box D4 like 4
Gene Alias	FOXD4b; FOXD4L2; bA460E7.2
Transcripts	ENSG00000184659
Virus	HPV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q8WXT5
HGNC ID	HGNC:23762
VEGA ID	OTTHUMG00000013337
OMIM ID	611085
String ID	9606.ENSP00000366630
PharmGKB ID	PA142671752

Target gene [FOXD4L4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5403683	chr9				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE51993 (GEO)	Cervical intraepithelial neoplasia	24	Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of FOXD4L4 expression and immune infiltrating cell level correlation result in HPV+ samples
FOXD4L4 expression: Low -> High

> Dataset: GSE51993
HeatMap of cell type fractions in all samples	Lollipop of FOXD4L4 expression and immune infiltrating cell level correlation result in HPV+ samples
FOXD4L4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).