HIV Target gene Detail Information

> FNBP4 Gene Search Result


Gene Information
Gene Name FNBP4
Gene ID 23360
Gene Full Name formin binding protein 4
Gene Alias FBP30
Transcripts ENSG00000285182
Virus HIV
Gene Type protein coding
HPA Location Info Nuclear speckles;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8N3X1
HGNC ID HGNC:19752
VEGA ID OTTHUMG00000166533
OMIM ID 615265
String ID 9606.ENSP00000263773
PharmGKB ID PA134971679
Target gene [FNBP4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4009208 chr11 6 6 12 View
4009319 chr11 11 1 12 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of FNBP4 expression and immune infiltrating cell level correlation result in HIV+ samples
FNBP4 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of FNBP4 expression and immune infiltrating cell level correlation result in HIV+ samples
FNBP4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).