HIV Target gene Detail Information

> FMR1 Gene Search Result

Gene Information

Gene Name	FMR1
Gene ID	2332
Gene Full Name	fragile X mental retardation 1
Gene Alias	POF; FMRP; POF1; FRAXA
Transcripts	ENSG00000102081
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q06787
HGNC ID	HGNC:3775
VEGA ID	OTTHUMG00000022606
OMIM ID	309550
String ID	9606.ENSP00000359506
PharmGKB ID	PA28191

Target gene [FMR1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013344	chrX	3	1		4	View
4013345	chrX	3	1		4	View
4013346	chrX	3	1		4	View
4013347	chrX	3	1		4	View
4015493	chrX	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FMR1 expression and immune infiltrating cell level correlation result in HIV+ samples
FMR1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).