HPV Target gene Detail Information

> FLT4 Gene Search Result


Gene Information
Gene Name FLT4
Gene ID 2324
Gene Full Name fms related tyrosine kinase 4
Gene Alias PCL; FLT-4; FLT41; LMPH1A; VEGFR3; VEGFR-3
Transcripts ENSG00000037280
Virus HPV
Gene Type protein coding
HPA Location Info Nuclear speckles;Plasma membrane;Cell Junctions;Predicted to be secreted;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins
Uniport_ID P35916
HGNC ID HGNC:3767
VEGA ID OTTHUMG00000130931
OMIM ID 136352
String ID 9606.ENSP00000261937
Drugbank ID BE0000023
Drug (Cytoscape Annotation) Pazopanib Hydrochloride;Vandetanib;Sunitinib Malate;Sorafenib Tosylate;Axitinib;Lenvatinib Mesylate
PharmGKB ID PA28183
FDA Approved Drug Sunitinib;Axitinib;Regorafenib
Target gene [FLT4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5403315 chr5 175 65 240 View

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).