HIV Target gene Detail Information

> FLT3LG Gene Search Result

Gene Information

Gene Name	FLT3LG
Gene ID	2323
Gene Full Name	fms related tyrosine kinase 3 ligand
Gene Alias	FL; FLG3L; FLT3L
Transcripts	ENSG00000090554
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins
Uniport_ID	P49771
HGNC ID	HGNC:3766
VEGA ID	OTTHUMG00000186490
OMIM ID	600007
String ID	9606.ENSP00000469613
PharmGKB ID	PA28182

Target gene [FLT3LG] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010456	chr19	9			9	View
4012938	chr19	1	3		4	View
4013257	chr19	2	2		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FLT3LG expression and immune infiltrating cell level correlation result in HIV+ samples
FLT3LG expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FLT3LG expression and immune infiltrating cell level correlation result in HIV+ samples
FLT3LG expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).