HIV Target gene Detail Information

> FLOT1 Gene Search Result

Gene Information

Gene Name	FLOT1
Gene ID	10211
Gene Full Name	flotillin 1
Transcripts	ENSG00000223654
Virus	HIV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;Plasma membrane;Vesicles;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	O75955
HGNC ID	HGNC:3757
VEGA ID	OTTHUMG00000004837
OMIM ID	606998
String ID	9606.ENSP00000365569
PharmGKB ID	PA28175

Target gene [FLOT1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000897	chr6	122	89	42	253	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FLOT1 expression and immune infiltrating cell level correlation result in HIV+ samples
FLOT1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FLOT1 expression and immune infiltrating cell level correlation result in HIV+ samples
FLOT1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).