HIV Target gene Detail Information

> FLI1 Gene Search Result

Gene Information

Gene Name	FLI1
Gene ID	2313
Gene Full Name	Fli-1 proto-oncogene, ETS transcription factor
Gene Alias	EWSR2; SIC-1; BDPLT21
Transcripts	ENSG00000151702
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors
Gene Function	Oncogene
Uniport_ID	Q01543
HGNC ID	HGNC:3749
VEGA ID	OTTHUMG00000165792
OMIM ID	193067
String ID	9606.ENSP00000433488
PharmGKB ID	PA28170

Target gene [FLI1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000830	chr11	55	112	102	269	View
4001179	chr11	23	42	135	200	View
4008398	chr11	13	2		15	View
4014346	chr11	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of FLI1 expression and immune infiltrating cell level correlation result in HIV+ samples
FLI1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of FLI1 expression and immune infiltrating cell level correlation result in HIV+ samples
FLI1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).