HIV Target gene Detail Information

> FKBP1A Gene Search Result


Gene Information
Gene Name FKBP1A
Gene ID 2280
Gene Full Name FKBP prolyl isomerase 1A
Gene Alias FKBP1; PKC12; PKCI2; FKBP12; PPIASE; FKBP-12; FKBP-1A
Transcripts ENSG00000088832
Virus HIV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID P62942
HGNC ID HGNC:3711
VEGA ID OTTHUMG00000031666
OMIM ID 186945
String ID 9606.ENSP00000383003
Drugbank ID BE0000695
PharmGKB ID PA28153
Target gene [FKBP1A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001723 chr20 28 66 42 136 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of FKBP1A expression and immune infiltrating cell level correlation result in HIV+ samples
FKBP1A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).